Abstract Search

ea0056oc5.2 | Diving deep into adrenal cortex diseases | ECE2018

Steroid profiling by liquid chromatography tandem mass spectrometry in a large cohort of patients with adrenal incidentalomas

Di Dalmazi Guido , Fanelli Flaminia , Zavatta Guido , Rinaldi Eleonora , Casadio Elena , Bitti Silvia Ricci , Mezzullo Marco , Vicennati Valentina , Pagotto Uberto

Background: Steroid profiling by mass spectrometry (MS) provided novel insights into the pathogenesis of adrenocortical tumors and hypercortisolism. The aims of the study were (I) to analyze the steroid profiling by liquid chromatography-tandem MS (LC-MS/MS) in a large cohort of patients with adrenal incidentalomas and (II) to investigate the relationship between steroid profile and clinical outcomes.Methods: We included 307 patients with mono- and bilat...

0 shares

ea0056p85 | Cardiovascular Endocrinology and Lipid Metabolism | ECE2018

Aortic root dilatation in primary aldosteronism: is treatment effective in reducing aortic damage?

Zavatta Guido , Dalmazi Guido Di , Pizzi Carmine , Rinaldi Eleonora , Casadio Elena , Bitti Silvia Ricci , Pasquali Renato , Pagotto Uberto , Vicennati Valentina

Introduction: Cardiovascular morbidity is more prevalent in primary aldosteronism (PA) than in essential hypertension. Preclinical studies have shown a possible association between ascending aorta dilatation and PA, probably mediated by the mineralocorticoid receptor.Patients and methods: A total of 84 patients attending the Endocrinology Unit of the S. Orsola-Malpighi University Hospital of Bologna, (Italy) were evaluated. Thirty-nine patients had a dia...

0 shares

Endocrine Abstracts

Steroid profiling by liquid chromatography tandem mass spectrometry in a large cohort of patients with adrenal incidentalomas

Aortic root dilatation in primary aldosteronism: is treatment effective in reducing aortic damage?

BiosciAbstracts